Just as scientific understanding of physics and biology has enabled creation of novel artifacts, materials, medicines and even novel organisms, so a scientific understanding of the brain will confer the ability not only to describe and characterize it but to modify it, diagnose and treat its illnesses, and eventually to imitate its operation. Computational neuroscience has as its twin goals the scientific understanding of how brain computes mind, and the engineering capability to reconstruct these identified mechanisms. Your brain is composed of low-precision, slow (milliseconds per operation), sparsely connected (p(connection) < 0.001) computing elements, yet it far outperforms any extant computer on tasks ranging from recognition to planning. This course will introduce concepts of brain circuit computation including anatomical circuit design, physiological operating rules, mathematical derivations, and comparative networks. Prerequisite: one of: Psyc 1, 6, Bio 34, Cosc 4, 5, Engs 20. 13F, Granger, 2A.