Human Pangenomics and the Future of Data Sharing

Engineering research seminar with Jonathan LoTempio, postdoctoral fellow at U Penn’s Perelman School of Medicine.

May 20, 2024
2:30 pm - 3:30 pm
Location
Spanos Auditorium, Cummings Hall
Sponsored by
Thayer School of Engineering
Audience
Public
More information
Amos Johnson

Optional ZOOM LINK
Meeting ID: 990 8011 6532
Passcode: 199304

The 6 May 2017 cover of The Economist proclaimed that data had supplanted oil as the new "most valuable resource." In a rhyme with the past where the early uses of oil were limited to straightforward activities like burning kerosene in lamps, so too the earlier days of big data as a resource were limited in their application. As oil lamps gave way to cars, planes, and plastics, the seven years that have passed since that cover story have seen the rapid development of new tools to use data from targeted advertisements, large language models, and the tracking of coronavirus evolution in real time. However, we do not interact with or produce data in the same way in every circumstance. Due to the regulations around performing medical research, human genomics offers a marvelous way to consider futures for data production, use, sharing, and protection.

In this seminar, I will discuss the chemistry and informatics that allowed the first reference genome to be created from one individual, and then look to the developments and innovations over the following decades that allow for the creation of more representative and inclusive human pangenomes. I will discuss my work on human genome assembly in collaboration with researchers in the Democratic Republic of the Congo and how this work points to a few possible futures for human genomics. Then we will consider, given the past, present, and future of reference genomics, how the limits of data use in genomics might inform consideration of human-data interaction in different spaces. 

Hosted by Professor Britt Goods.

Cosponsored by Thayer's Office of Diversity, Equity, and Inclusion.

Location
Spanos Auditorium, Cummings Hall
Sponsored by
Thayer School of Engineering
Audience
Public
More information
Amos Johnson